Aiming at the problem that grinding wheel wear will seriously affect the aspheric grinding quality, the formulas of material removal volume and grinding wheel wear volume in aspheric grinding process are analyzed based on the motion mode of aspheric grinding.The wear law of arc-sharped diamond grinding wheel for aspheric grinding is studied by combining with grinding wheel wear test.The results show that the radial dimension of arc-sharped diamond grinding wheel decreases due to wear during aspheric grinding, and there are three main stages of its diameter change before the failure of the grinding wheel, namely rapid change stage, slow change stage and micro change stage. Besides, the holding force of the bond to diamonds in the top of arc is less than those of other diamonds because of structural characteristics of arc-sharped wheel, which leads to rapid wear of diamond abrasives and bond until the holding force is not affected by the characteristics of arc-sharped wheel. At that time, the wear process of arc-sharped wheel is similar as the wear process of the plane wheel.